Stimulation of a liver cell by glucagon

How would you expect a nonhydrolyzable GTP analogue to affect signaling events that take place during the stimulation of a liver cell by glucagon? What would be the effect of the same analogue on signal transduction of an epithelial cell after exposure to epidermal growth factor (EGF)? How would this compare to the effects of the cholera toxin on these same cells?

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...P subunit dissociates from the beta/gamma subunits and contacts an effector enzyme like adenylyl cyclase. This in turns leads to the production of a second messenger, cAMP. cAMP then activates enzymes that regulate the enzymes that regulate the conversion of glucose to glucagon and vice versa. The important part here is that when the alpha-GTP contacts adenylyl cyclase it hydrolyses the GTP ...