Sadness and Clinical Depression

What are the differences between 'normal' and maladaptive behaviors and behavior patterns specifically with sadness and clinical depression?

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... Sometimes the person cannot get out of bed or cannot sleep or sleeps too much; or cannot stop crying.
When an individual experiences a discrete episode of persistent and pervasive emotional depression, Major Depressive Episode may be applied. The individual may be diagnosed with one of the Mood Disorders, either Major Depressive Disorder or a Bipolar Disorder.

According to DSM-IV-TR, the 'maladaptive?behavioral criteria for a Major Depressive Episode include:

A. Five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either

(1) depressed mood or
(2) loss of interest or pleasure.

Note: Do not include symptoms that are clearly due to a general medical condition, or mood-incongruent delusions or hallucinations.

(1) depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g., feels sad or empty) or observation made by others (e.g., appears tearful). Note: In children and adolescents, can be irritable mood.
(2) markedly diminished interest or pleasure in all, or almost all, activities most of the ...